Involvement of pancreatic and bile ducts in autoimmune pancreatitis

Autoimmune pancreatitis mimicking pancreatic tumor

Autoimmune pancreatitis (AIP) is a rare disease of unknown pathomechanism. AIP belongs to the IgG4-related disease family and responds well to steroids, although the relapse rate can reach up to 20-30%. Differentiation of AIP from the more common pancreatic cancer can be very challenging. About 20% of autoimmune pancreatitis is diagnosed postoperatively during final histological examination. Wh...

Pancreatic Tuberculosis or Autoimmune Pancreatitis

Introduction. Isolated pancreatic and peripancreatic tuberculosis is a challenging diagnosis due to its rarity and variable presentation. Pancreatic tuberculosis can mimic pancreatic carcinoma. Similarly, autoimmune pancreatitis can appear as a focal lesion resembling pancreatic malignancy. Endoscopic ultrasound-guided fine needle aspiration provides an effective tool for differentiating betwee...

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.

Ductal occlusion has been postulated to precipitate focal pancreatic inflammation, while the nature of the primary occluding agents has remained elusive. Neutrophils make use of histone citrullination by peptidyl arginine deiminase-4 (PADI4) in contact to particulate agents to extrude decondensed chromatin as neutrophil extracellular traps (NETs). In high cellular density, NETs form macroscopic...

Autoimmune pancreatitis: pancreatic and extrapancreatic imaging findings.

OBJECTIVE The purpose of this article is to discuss the systemic nature of autoimmune pancreatitis and its various pancreatic and extrapancreatic imaging findings. CONCLUSION Autoimmune pancreatitis is a systemic disease with a wide range of pancreatic and extrapancreatic imaging findings. These findings can mimic those of other diseases in the pancreas or other organs and therefore are commo...

Autoimmune pancreatitis, pancreatic cancer and immunoglobulin-G4.